Labs

DeBiasi Laboratory

About the Lab

Roberta DeBiasi's, MD, MS, research expertise includes basic science and clinical/translational research. She serves as principal investigator for research and clinical trials focusing on severe and emerging infections affecting normal children, immunocompromised hosts, neonates and pregnant women. Specific areas of research focus include: NIAID/NIH Congenital and Perinatal Infection Consortium funding to study natural history and novel treatments for congenital cytomegalovirus infection, neonatal herpes simplex virus, enterovirus and parechovirus infection. She co-directs the Congenital Infection Program at Children's National Hospital, which includes research protocols in the U.S. and internationally focused on prenatal imaging, testing, genetics and virologic aspects of congenital infection. Her research portfolio includes studies focused on treatment and long-term outcomes of Lyme disease and COVID infection in children, as well as Kawasaki Disease. She is also involved in emergency investigational new drug (IND) acquisition of agents for the treatment of severe viral myocarditis, encephalitis and malaria.

  • Lab Focus Areas

    Congenital viral infection

    Emerging infectious diseases

    Lyme and tick-borne disease


  • Partnerships

    Infectious Diseases Division

    NIH Congenital and Perinatal Infection Consortium

    NIAID-CNH Research Partnership

    Lyme Clinical Trials Network

  • Contact

    Roberta DeBiasi, MD, MS Chief, Division of Pediatric Infectious Diseases, Robert H. Parrot Professor of Pediatric Research

Featured Publications

  • Plasma cell-free RNA signatures of inflammatory syndromes in children

    Loy CJ, Servellita V, Sotomayor-Gonzalez A, Bliss A, Lenz JS, Belcher E, Suslovic W, Nguyen J, Williams ME, Oseguera M, Gardiner MA; P.E.M.K.D.R.G.; C.H.A.R.M.S. the Study Group; Choi JH, Hsiao HM, Wang H, Kim J, Shimizu C, Tremoulet AH, Delaney M, DeBiasi RL, Rostad CA, Burns JC, Chiu CY, De Vlaminck I. PMID: 39240972. Proc Natl Acad Sci USA 0;121(37):e2403897121 Sept 6 2024

  • Pediatric Lyme disease: systematic assessment of post-treatment symptoms and quality of life

    Monaghan M, Norman S, Gierdalski M, Marques A, Bost JE, DeBiasi RL. PMID: 36997691. Pediatr Res. 95(1):174-181. Jan 2024

  • Oral Valganciclovir Initiated Beyond 1 Month of Age as Treatment of Sensorineural Hearing Loss Caused by Congenital Cytomegalovirus Infection: A Randomized Clinical Trial

    Kimberlin DW, Aban I, Peri K, Nishikawa JK, Bernatoniene J, Emonts M, Klein N, Bamford A, DeBiasi RL, Faust SN, Jones CE, McMaster P, Caserta M, Ahmed A, Sharland M, Demmler-Harrison G, Hackett S, Sánchez PJ, Shackley F, Kelly D, Dennehy PH, Storch GA, Whitley RJ, Griffiths P; Collaborative Antiviral Study Group (CASG) PMID: 38309519. Journal of Pediatrics 268:113934 May 2024

  • Outcomes up to age 36 months after congenital Zika virus infection-U.S. states

    Neelam V, Woodworth KR, Chang DJ, Roth NM, Reynolds MR, Akosa A, Carr CP, Anderson KN, Mulkey SB, DeBiasi RL, Biddle C, Lee EH, Elmore AL, Scotland SJ, Sowunmi S, Longcore ND, Ahmed M, Langlois PH, Khuwaja S, Browne SE, Lind L, Shim K, Gosciminski M, Blumenfeld R, Khuntia S, Halai UA, Locklear A, Chan M, Willabus T, Tonzel J, Marzec NS, Barreto NA, Sanchez C, Fornoff J, Hale S, Nance A, Iguchi L, Adibhatla SN, Potts E, Schiffman E, Raman D, McDonald MF, Stricklin B, Ludwig E, Denson L, Contreras D, Romitti PA, Ferrell E, Marx M, Signs K, Cook A, Leedom VO, Beauregard S, Orantes LC, Cronquist L, Roush L, Godfred-Cato S, Gilboa SM, Meaney-Delman D, Honein MA, Moore CA, Tong VT. PMID: 37658124; PMCID: PMC10913023. Pediatr Res 2024 Jan;95(2):558-565. Jan 2024

  • Pediatric SARS-CoV-2 long term outcomes study (PECOS): cross sectional analysis at baseline

    Montealegre Sanchez GA, Arrigoni LE, Yonts AB, Rubenstein KB, Bost JE, Wolff MT, Barrix MC, Bandettini WP, Boateng B, Bulas DI, Burklow TR, Carlyle KP, Chen M, Das S, Dewar RL, Dixon AA, Edu MA, Falik RL, Geslak ML, Gierdalski M, Harahsheh AS, Herbert LJ, Highbarger J, Huq SR, Ko A, Koumbourlis AC, Lacey SR, Lipton AJ, Monaghan M, Ndour AS, Olivieri LJ, Pillai DK, Rehm CA, Sable CA, Sachdev V, Thurm AE, Truong UT, Turkbey EB, Vilain E, Weyers S, White JS, Williams AA, Zember J, Liang CJ, Delaney M, Batshaw ML, Notarangelo LD, Wessel DL, Barron K, DeBiasi RL PMID: 39695262. Pediatr Res. 98(2):541-550. Aug 2025
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