District of Columbia Intellectual and Developmental Disabilities Research Center
About Us
The District of Columbia Intellectual and Developmental Disabilities Research Center (DC-IDDRC) conducts multidisciplinary, basic, translational, clinical and community research in intellectual and developmental disabilities (IDDs). Our mission is to expand the understanding of the causes underlying IDDs, develop innovative therapies, and prevent or attenuate the full effects of these disorders, so that each child can achieve her/his full physical and intellectual potential.
Children’s National Hospital (lead institution) has played a crucial role in bringing together four major academic institutions in D.C. – Children’s National, the George Washington University, Georgetown University and Howard University – to create, grow and sustain a vigorous center and a supportive environment for IDD investigators.
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Major Themes
Neural development and neurodevelopmental disorders
Fetal and neonatal brain injury
Genetic disorders
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Contact
Nikkie Adesida Senior Research Center Manager [email protected]
Featured Publications
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Impaired in vivo feto-placental development is associated with neonatal neurobehavioral outcomes
Andescavage N, Bullen T, Liggett M, Barnett SD, Kapse A, Kapse K, et al. Pediatric Research 93(5):1276-1284. doi: 10.1038/s41390-022-02340-0 April (2023) -
Severity of prematurity and age impact early postnatal development of GABA and glutamate systems
Basu SK, Pradhan S, Sharker YM, Kapse KJ, Murnick J, Chang T, et al. Cerebral Cortex 33(12):7386-7394. doi: 10.1093/cercor/bhad046 June (2023) -
Early Endosomes Undergo Calcium-Triggered Exocytosis and Enable Repair of Diffuse and Focal Plasma Membrane Injury
Bittel DC, Jaiswal JK., Advanced Science 10(33):e2300245. doi: 10.1002/advs.202300245 November (2023) -
Limbic network co-localization predicts pharmacoresistance in dysplasia-related epilepsy
Cohen NT, Chang P, Gholipour T, Oluigbo C, Vezina LG, Xie H, et al. Annals of Clinical and Translational Neurology 10(11):2161-2165. doi: 10.1002/acn3.51892 November (2023) -
Experience of early-life pain in premature infants is associated with atypical cerebellar development and later neurodevelopmental deficits
Cook KM, De Asis-Cruz J, Kim JH, Basu SK, Andescavage N, Murnick J, et al. BMC Medicine 21(1):435. doi: 10.1186/s12916-023-03141-w November (2023)