Labs
Hsiao Laboratory
About the Lab
We study brain circuits that integrate both motor and cognitive functions. Our lab focuses on the biochemistry and physiology that occur at synapses and circuits during learning, which is essential for memory, motor and social behaviors. We also develop tools for functional discovery and manipulation of neuronal properties (genetic perturbation and optogenetic) for studying how these manipulations affect function using in vivo brain recordings in awake animals.
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Lab Focus Areas
Intellectual and Developmental Disabilities
Cerebellar Neural Circuits and Behavior
Autism Spectrum Disorders
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Partnerships
Institute of Biomedical Sciences, George Washington University
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Contact
Katie Hsiao, Ph.D. Principal Investigator [email protected]
- External Lab Site
Featured Publications
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A Thalamic Orphan Receptor Drives Variability in Short Term Memory
Hsiao K, Noble C, Pitman W, Yadav N, Kumar S, Keele GR, Terceros A, Kanke M, Conniff T, Cheleuitte-Nieves C, Tolwani R, Sethupathy P, Rajasethupathy P. doi:10.1016/j.cell.2020.09.011; PMCID: PMC7572771. Cell 183(2):522-536.e19. (2020) -
Cyfip1 Regulates Presynaptic Activity during Development
Hsiao K, Harony-Nicolas H, Buxbaum JD, Bozdagi-Gunal O, Benson DL. J Neurosci. 2016;36(5):1564-1576. (2016) -
Axonal cap-dependent translation regulates presynaptic p35
Hsiao K, Bozdagi O, Benson DL. doi:10.1002/dneu.22154; PMCID: PMC4136430. Dev Neurobiol. 74(3):351-364. (2014)