Hsiao Lab

About the Lab

Bridging Genes and Behavior: Our Quest to Translate Neuroscience into Therapeutics

Dr. Hsiao’s research focuses on synapse plasticity, learning and memory. Her Ph.D. thesis studies molecular mechanisms of inherited mutations that cause neurodevelopmental disorders at Icahn School of Medicine at Mount Sinai. In postdoctoral research at Rockefeller University, she investigated the complex relationship between genetic factors and neural circuit dynamics related to working memory processes. Her work developed functional assays on primary neuron cultures, ex vivo brain slices, and viral genetic control of nervous system function at the Allen Institute for Brain Science. Dr. Hsiao’s current work studies the impact of genetic variants on cognitive function and learning motor skills. As a PI or co-Investigator on several university- and private- funded grants (including the Rockefeller University Women & Science Initiative and the Robertson Therapeutic Development Fund), Dr. Hsiao applied in vivo optophysiology brain recording and genomic analysis to study how genetic diversity contributes to variation in cognition.