Our Research

CellBuilder™

Expanding Access to Potentially Life-Saving Cell and Gene Therapies

CellBuilder™ is a turnkey solution developed by the Cellular Therapy Laboratory at Children’s National Hospital to help academic centers and hospitals establish or expand cell and gene therapy programs efficiently, safely and cost-effectively.

Built on Children’s National’s extensive experience in GMP manufacturing, clinical trial support, regulatory submissions, quality systems, and multicenter cell therapy clinical trial implementation, CellBuilder™ provides the infrastructure, tools, training and advisory support needed to accelerate program development and bring advanced therapies closer to patients.

Programs and Services

CellBuilder™ offers customizable modules and services based on each institution’s needs, including:

Cell Therapy Program Modules

  • Virus-specific T cells
  • Tumor-associated antigen specific T cells
  • CAR T cells
  • Mesenchymal stromal cells
  • Hematopoietic stem cell cryopreservation

Services Offered

  • Non-exclusive licensing of existing technologies of interest including associated protocols, SOPs, templates and related program materials
  • Facility and infrastructure assessment
  • GMP advisory services
  • Manufacturing process technology transfer
  • Hands-on and virtual training for manufacturing, QA/QC and program leadership teams
  • Regulatory and clinical research support, including IND/CMC preparation, protocol development, responses to FDA queries and annual reporting support
  • Review of critical SOPs, protocols, training materials and manufacturing data

Why CellBuilder™

CellBuilder™ is designed to help institutions reduce the time, cost, and risk associated with building cell and gene therapy capabilities. By leveraging established experience, proven workflows, and practical implementation support, CellBuilder™ enables programs to treat patients locally, strengthen institutional clinical trial infrastructure, and support future development of novel therapies.

Graphic reading: Program template, Protocol template, SOPS; Environment and Tools, Modular cleanroom, equipment, materials; Regulatory support, CMC guidance, advisory; Training. CellBuilder™.

Contact Us

To learn more about CellBuilder™ or discuss potential collaboration, please contact us.

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